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Some real-world cohorts and long-term extension trials have reported comparable efficacy of biologic agents across BMI categories, especially when weight-based dosing regimens or dose optimization strategies were applied
In key trials, it demonstrated weight reduction of 1821% depending on study design and patient group
By Natalie Burg Digital Writer Jun 12, 2026 - 5 min read Key Takeaways Weight management is a long-term, multistep journey and practices that coordinate referrals, follow-up and ongoing monitoring can improve continuity and help reduce patient drop-off
Comparative Analysis and Place in Therapy The American Diabetes Association (ADA) and the American Association of Clinical Endocrinologists (AACE) have progressively updated their guidelines to reflect the growing evidence for newer antidiabetic agents
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