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MOTS-c is not FDA-approved and long-term human safety data does not exist
Briani C, Dalla Torre C, Citton V, et al
The constant itching and discomfort can disrupt sleep patterns, leading to fatigue and irritability
Because independent long-term human trials are limited for the injectable options, unknown risks cannot be ruled out
Giving them more frequently than the established schedule is a form of over-treatment that is not supported by evidence and can strain healthcare resources (nurses time, clinic space, and medication supplies)
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