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Zamani, A.N
PepT1 is a di/tripeptide transporter normally expressed in the small intestine and induced in the colon during inflammatory bowel disease
Higher doses produce increased incidence and severity of gastrointestinal symptoms, which explains why clinical protocols use gradual dose escalation starting at 0.25 mg weekly and incrementally increasing every 4 weeks
Timing: No strict timing requirement between the two
Ohashi and Fukada, 2019)
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