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Menopause and hormonal shifts: Hormonal changes, especially declining estrogen, can slow metabolism, increase fat storage, and reduce muscle mass, all of which make weight loss harder

You need a BMI of 30 or above, or a BMI of 27 or above with at least one weight-related condition such as type 2 diabetes, high blood pressure, or high cholesterol

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While usually mild to moderate in severity, persistent or severe constipation requires attention, as it can progress to faecal impaction or, in rare circumstances, contribute to more serious complications

Steven Swengel Board-Certified Dermatologist Since establishing RefinedMD in 2012, Dr