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Endoplasmic reticulum stress and oxidative stress The accumulation of lipotoxic speciesincluding free fatty acids (FFAs), diacylglycerols, phospholipids, and free cholesteroltriggers endoplasmic reticulum (ER) stress, leading to activation of multiple cellular stress pathways

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Natural Killer (NK) cells are a critical component of the innate immune system, responsible for identifying and destroying virally infected cells and early-stage malignancies