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10.1038/s41598-021-88612-x 37 KazankovK.JrgensenS
Tirzepatide (a GLP-1R/GIPR dual agonist), licensed by the MHRA as Mounjaro for type 2 diabetes and, subject to NICE guidance, for weight management in adults with obesity, achieved mean weight reductions of up to approximately 22% in the SURMOUNT-1 trial (NEJM 2022) a notable improvement over GLP-1R monotherapy
Similar content being viewed by others Introduction Cardiovascularkidneymetabolic (CKM) syndrome encompasses a group of interrelated conditions, including obesity, type 2 diabetes (T2D), cardiovascular disease (CVD), and chronic kidney disease (CKD), significantly contributing to premature morbidity and mortality worldwide [1, 2]
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