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Reported to act on fat-cell metabolism without stimulating IGF-1 production, distinguishing it from full GH in preclinical work
No human clinical trials have been completed
This may be due to patients being in the early stages of ALS and not showing rapid progression, the team noted
Also available as a high-dose option
This pattern aligns with B12 pharmacokinetics: serum levels peak 8-12 hours post-injection, tissue saturation occurs over 48-72 hours (Andrs et al., Journal of Blood Medicine , 2018)
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