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Novo Nordisk and Eli Lilly have positioned themselves at the forefront of this space with their blockbuster GLP-1 receptor agonist drugs Ozempic, Wegovy, and Rybelsus from Novo Nordisk, and Mounjaro and Zepbound from Lilly targeting both Type 2 diabetes and obesity
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The authors of Weighing the Impacts of GLP-1s: Quasi-Experimental Evidence from Provider Adoption acknowledge support from the Department of Veterans Affairs Office of Academic Affiliations Advanced Fellowships, and Jasmin Moshfegh acknowledges support from The Big Data Scientist Training Enhancement Program
Some studies have shown reductions in systemic inflammatory markers such as C-reactive protein (CRP) in patients taking GLP-1 medications, though whether this translates to clinically meaningful joint pain reduction independent of weight loss is not definitively established
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