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This tiredness may relate to reduced caloric intake, gastrointestinal side effects, or metabolic adaptation
In addition, the STEP trials examined the impact of semaglutide on weight-related complications and potential benefits beyond weight loss
They use the same active ingredient: tirzepatide
For a detailed breakdown, see our guide on what to expect after your first tirzepatide dose
The STEP trials reported nausea in approximately 44% of participants on semaglutide 2.4 mg versus 17.4% on placebo
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