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Beyond the demonstration that pharmacologic blockade of IGF-1R signaling can favorably impact lifespan, these data also provide new insights into temporal and metabolic aspects regarding this pathway and aging
doi:10.1016/j.nutres.2018.11.012
NNMTi-mediated changes to the availability of nicotinamide/nicotinic acid in conjunction with the presence of moderate amounts of Lactobacillus may promote a positive feedback loop further increasing the abundance of Lactobacillus
Methods We conducted a population-based propensity-matched retrospective cohort study using TriNetX
2011;17(12):CR677-CR682
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