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The FDA labels advise that these medications have not been studied in patients with prior pancreatitis, and acute pancreatitis has been observed in clinical trials and post-marketing reports

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Methods We identified genetic proxies of the effect of GLP-1R, GIPR, and GCGR by combining Mendelian randomization (MR), Bayesian colocalization, and linkage disequilibrium (LD) analyses

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Koshibu M, Mori Y, Saito T, Kushima H, Hiromura M, Terasaki M, Takada M, Fukui T, Hirano T