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Diabetes Obes Metab (2021) 23(3):75462
Claims that either route is superior go beyond the available data
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The main barriers are bioavailability (how much drug actually enters the bloodstream), stability (peptides degrade when exposed to skin temperature and enzymes), and patient compliance (patches still require weekly changes and site monitoring)
Furthermore, recent evidence on the activity of brown algal phlorotannins showed not only highly significant anti- Salmonella activity but also longer food shelf life when added to alginate-based nanofiber packaging (Surendhiran et al., 2019)
PYY is a peptide released from colonic EECs in response to nutrients, with PYY3-36 being the most prevalent form of this gut peptide in the circulation 198,199
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