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This is important for overall health and well-being

Despite an increased activity of GPx, GR enzymes in C

Platelet lysate therapy attenuates hypoxia induced apoptosis in human uroepithelial SV-HUC-1 cells through regulating the oxidative stress and mitochondrial-mediated intrinsic apoptotic pathway

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First, mechanistic studies should combine single-cell spatial transcriptomics with mitochondrial metabolomics to map ferroptosis pathways in spinal ventral horn motor neurons, microglia, and astrocytes, with emphasis on the coupling between NCOA4-mediated ferritinophagy and SOD1/TDP-43 clearance, thereby establishing a dynamic model linking mitochondrial iron dysregulation, proteotoxic stress, and cell death