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In late 2024, tirzepatide (Zepbound) became the first GLP-1 and first medication to be approved for sleep apnea

Similarly, in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mouse model, GLP-1 analogues were reported to protect the brain from MPTP-induced pathological effects, such as movement disorders, increased levels of -synuclein, chronic inflammation in the brain, loss of dopaminergic neurons, oxidative stress, and expression of growth factors (65)

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Researchers observed this difference during meal challenge tests and when the dogs were fasting