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Youdim recommends that people who take these drugs be under the care of a physician to watch for side effects, which can include too much or rapid weight loss, which is not considered safe or healthy
These therapies are especially helpful when used alongside testosterone replacement therapy and GLP-1 medications like semaglutide (Ozempic) or tirzepatide (Zepbound), where supporting muscle, hydration, and nutrient status becomes even more important
Berberine is not part of these evidence-based pathways
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Higher-dose versions like Wegovy and Zepbound have received FDA approval specifically for obesity, fueling a market expected to boom from $2.8 billion in 2022 to over $100 billion by 2030
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