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In the context of Alzheimer's disease, reduced lactylation of tau at K677 inhibits ferroptosis by disrupting ferritinophagy, resulting in dysregulated iron metabolism and increased resistance to cell death (119)
doi: 10.1038/s41467-024-49186-0 60 KapoorMMartel-PelletierJLajeunesseDPelletierJPFahmiH
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