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Oxidative RNA damage can impair protein translation, and damaged RNA can degrade prematurely, further impairs the synthesis of essential proteins (65)
Several anticancer drugs that inhibit nucleotide metabolism induce apoptosis
But for someone with 40, 60, or 80+ lb to lose, the difference between a 14.9% and 24.2% average outcome is enormous in practical terms and potentially transformative for metabolic health markers
Cell 99 NencioniL.De ChiaraG.SgarbantiR.AmatoreD.AquilanoK.MarcocciM
Curr Opin Physiol
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