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Some patients may continue medication long term, some may use a clinician-guided maintenance strategy, and others may stop because of side effects, access, pregnancy planning, or personal medical factors

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These peptides initially stimulate hormone release but subsequently suppress gonadotropin production through receptor downregulation, effectively reducing sex hormone levels that fuel certain cancers

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Imipramine blocks ethanol-induced ASMase activation, ceramide generation, and PP2A activation, and ameliorates hepatic steatosis in ethanol-fed mice