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In addition, it will be of interest to understand whether the carnitine shuttle plays a role in compensating for ACLY and ACSS2 under conditions such as high fat diet, in which both enzymes are suppressed in adipose tissue 43

Beyond its role in transporting fatty acids, L-carnitine is involved in other important physiological processes

The subcutaneous administration of liraglutide not only improves hyperglycemia and peripheral IR but also reverses insulin signaling impairment in the brain, leading to decreased AD-associated tau hyperphosphorylation [60]

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