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JAMA Network Open, 7(1), e2350408
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People with cancer People with a history of the disease should avoid HGH treatment, as it can stimulate cell growth, including disease cells
The TRIUMPH-4 safety profile is qualitatively similar to semaglutide and tirzepatide (GI adverse events dominate) but the rate of nausea, vomiting, and diarrhea is higher than previously seen in the class, and dropout at 12 mg is higher than at 9 mg
These studies suggest that unique KP alterations may underlie specific clinical syndromes and highlight the potential of KP metabolites as diagnostic biomarkers and potential contributors to neuropathology
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