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Before starting Janumet, doctors assess kidney function, which may be contraindicated in severe cases
The oral formulation appears to be bringing new patients into treatment rather than simply shifting share among existing users
Moderate alcohol consumption may be acceptable for some individuals on GLP-1 receptor agonists
In addition, IL-1, a cytokine known to enhance oxidative stress in the CNS, has been found to exert protective effects on both astrocytes and neurons by modulating GSH synthesis 88
For example, an employer might allow Wegovy with a $150 monthly copay under pharmacy benefits if the employee has a documented BMI35, but disallow it if BMI =35), documented lifestyle program participation, specialist prescribing, etc
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