Michael Uzmann, a physician dual board-certified in internal medicine and endocrinology, the results of this study arent surprising, given that we know from previous research that the GLP-1 semaglutide has the same effect when combined with MHT
Participants were monitored for 72 weeks with regular blood work, vital signs, and adverse event documentation
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A 2025 meta-analysis published in PMC pooling data from over 140,000 participants found that tirzepatide produced an average of 4.23 percentage points more weight loss than semaglutide across both clinical trials and real-world settings (source)
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