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The potential value of combining these therapies lies in addressing overlapping cardiorenal and metabolic risk pathways as available evidence for dual therapy in HF populations remains limited and is derived largely from subgroup analyses, observational studies, and extrapolation from diabetes or obesity trials rather than dedicated HF randomized trials [24, 25, 27, 30, 50]
More research is needed to fully understand its efficacy for weight loss in adults experiencing mental illness
If symptoms persist beyond the early titration period, temporary dose stabilization or dose reduction should be considered
Rarely, this systemic inflammatory condition can increase the risk of trigeminal neuralgia
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