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Glutathione is a natural antioxidant found in the body, composed of three amino acids: cysteine, glutamine, and glycine
It reduces hepatic glucose production, in part through effects on mitochondrial metabolism and activation of AMP-activated protein kinase (AMPK), an enzyme that plays a crucial role in cellular energy homeostasis
A study that looked at 0.5-1mg/kg/day leucovorin in patients with cerebral folate deficiency (and related neurological symptoms) found that 90% of those supplemented achieved normal 5-methyltetrahydrofolate cerebral spinal fluid concentrations
doi:10.1021/acs.nanolett.9b03245 208
Cell 177 , 13301345.e1318 (2019)
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