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For example, one small trial reported about half of children improved on at least two measures

Contrasting health effects of bacteroidetes and firmicutes lies in their genomes: Analysis of P450s, ferredoxins, and secondary metabolite clusters

JCI insight 4 , e132975 (2019)

Acta Physiol Plant 38(9):110

Noteworthy, a widespread reduction in salt intake on the one hand, and the frequent replacement of iodized salt by so-called whole salts (such as Himalayan pink salt), perceived as healthier alternatives, on the other hand, has contributed to the re-emergence of iodine deficiency in industrialized countries, with adverse health consequences, especially in children [47,48,49]