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Dull and tired-looking skin can develop because of stress, poor sleep, dehydration, sun exposure, unhealthy food habits, pigmentation, or lack of proper skin care

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Strong adoption of advanced GLP-1 therapies by healthcare providers, coupled with growing clinical evidence supporting cardiovascular and weight-loss benefits, is driving market demand

The Kaiser Family Foundation reported in May 2025 that 12% of its nearly 1,500 survey respondents, including 20% of women, had filled at least one prescription for GLP-1 drugs

GLP-1-based therapies and resmetirom operate through distinct and potentially complementary mechanisms: while resmetirom exerts direct hepatic effects by activating THR- to enhance mitochondrial function, reduce hepatic lipogenesis, and promote lipid oxidation specifically in hepatocytes, GLP-1 RAs and multi-agonists address the upstream metabolic drivers of MASLD including insulin resistance, obesity, and systemic inflammation