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Clinical trials involving retatrutide in the UK are subject to oversight under the Medicines for Human Use (Clinical Trials) Regulations 2004 and require MHRA clinical trial authorisation
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That breadth matters because phase 3 trials test efficacy and safety in larger, more representative populations than phase 2 and weight-loss figures often moderate as populations widen
Semaglutide, the active ingredient in Wegovy and Ozempic, belongs to a class of drugs that mimic glucagon-like peptide-1, a hormone the gut releases after eating
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