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The clinical evidence for some of these agents (like SGLT2 inhibitors and statins) in improving cardiovascular outcomes is strong, supporting the concept that modulating pathways intertwined with oxidative stress is a viable therapeutic approach

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CSCs possess a strong ability to evade programmed cell death induced by detachment (known as anoikis), allowing them to survive under adverse metastatic conditions characterized by extracellular matrix (ECM) deprivation, which is promoted during chemotherapy or radiotherapy [181]

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Case Rep

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Huang, Y, Cai X, Qiu M, et al

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Melo MCA, Abreu RLC, Linhares Neto VB, de Bruin PFC, de Bruin VMS

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