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This absence of hyperglycemic effects makes the peptide safer for individuals concerned about glucose metabolism, and the lack of IGF-1 elevation reduces theoretical concerns about cell proliferation

Silverstein said he decided to investigate the over-prescribing of B12 shots, because "as an internal medicine resident, I have seen many patients come into the emergency department, and they were getting B12 injections without having a really good reason for it." His study could not determine why family physicians were prescribing it inappropriately including whether it was initiated by the doctor or at the request of the patient

However, exclusive use of folic acid in treating vitamin B12 deficient megaloblastic anemia could result in progressive and irreversible neurologic damage

These lipotropic shots are made of 1 vitamin and three key amino acids