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From a neuropsychiatric perspective, I would add that, in my opinion, this class of medications might also prove efficient for the treatment of acute manic episodes in bipolar disorder

Vehicle-treated Gipr fl/fl and Gipr Syn/ mice showed a 1.5% and 2.6% weight gain, respectively, whereas mGIPR-Ab/P1-treated Gipr fl/fl mice lost 20% of their body weight (Fig

Researchers are continuing their work

So it's the same hormone but at amplified amounts they now hear or feel the fullness and they actually start to reduce their body weight

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