Vasodilatory actions of glucagon-like peptide 1 are preserved in skeletal and cardiac muscle microvasculature but not in conduit artery in obese humans with vascular insulin resistance
A single-center randomized trial in Germany investigated the effects of catheter ablation versus medical therapy in 363 HFrEF patients with AF
Urban tertiary hospital studies indicate even higher rates, frequently ranging from 31% to 45%, reflecting lifestyle transitions, socioeconomic factors and reduced physical activity in metropolitan areas. Obesity contributes to a spectrum of complications including type 2 diabetes mellitus, hypertension, dyslipidemia, coronary artery disease, osteoarthritis, obstructive sleep apnea and non-alcoholic fatty liver disease, thereby increasing all-cause mortality and posing significant public health challenges[4]
TRIUMPH-4 Results (December 2025): The First Phase 3 Data TRIUMPH-4 was the first Phase 3 trial to read out and the first concrete look at retatrutide's efficacy outside the Phase 2 cohort
XYRHCX2021011), the Suzhou Science & Technology Town Hospital pre-research fund project (no