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In a follow-up study, the same group demonstrated that HPDL deficiency induces a lethal form of mitochondrial encephalopathy and, importantly, supplementation with HPDL-derived intermediates (4-HMA or 4-HB) was sufficient to alleviate disease symptoms
A separate pilot study on aged skin reported thicker skin, more elasticity, better hydration, and more collagen production
The good news is that heart palpitations are usually harmless
doi: 10.3390/biom11121843 52
The article also highlights preclinical findings, possible mechanisms of action, safety considerations, and common FAQs to help readers understand its therapeutic potential
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