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Before ferroptosis-targeted treatments become part of routine diabetes care, large clinical trials will need to confirm both safety and long-term benefit

Simultaneously, it enhances M2-like features, including the secretion of VEGF, a key factor in angiogenesis, while inhibiting the expression of other M2 markers like CD206 (MRC1)

Since YAP1 served as a co-transcription factor for the classical driver of cancer glycolysis-HIF1, we then sought to examine whether exogenous HEXB could activate YAP1/HIF1 to facilitate endogenous HEXB transcription