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Both the / hydrolase and -propeller domains participate in inhibitor binding

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It is prescribed for adults with obesity (defined as a body mass index, or BMI, of 30 or higher) or those with a BMI of 27 or higher who have weight-related health issues such as high blood pressure or cholesterol

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Science-Backed GLP-1 medications, like Zepbound are FDA-approved for type 2 diabetes and have proven effective for weight loss