Pay in 4 interest-free payments of $7.27 Learn more
Ships within 48 hours · Estimated delivery Aug 19 - Aug 24
This peptide has been explored in cellular signalling research focused on cytoprotection, cell proliferation, and inflammation pathways (Wikipedia: BPC-157)
The 28-day rule Standard guidance recommends using reconstituted semaglutide within 28 days of mixing
5-Amino-1MQ Key Research Facts Chemical name: 5-Amino-1-Methylquinolinium (also abbreviated as 5A-1MQ or 5MQ) Target enzyme: Nicotinamide N-Methyltransferase (NNMT) Mechanism: Competitive inhibition of NNMT reduces 1-MNA production, preserves nicotinamide for NAD+ synthesis and SAM for epigenetic methylation Selectivity: High selectivity for NNMT does not inhibit related SAM-dependent methyltransferases or NAD+ salvage pathway enzymes Membrane permeability: High passive and active transport permeability confirmed in PAMPA and Caco-2 cell assays NNMT expression: Upregulated in obese adipose tissue, multiple cancer types, and aged skeletal muscle tissue contexts of primary research interest Downstream targets: NAD+ availability, SIRT1/SIRT3 activity, SAM-dependent epigenetic methylation, lipogenesis, energy expenditure Pre-clinical models: Diet-induced obese (DIO) mice, 3T3-L1 adipocyte cell models, aged mouse skeletal muscle models, HeLa cancer cell lines In vitro cell viability: No impact on cell viability at 10 M concentration in 3T3-L1 pre-adipocytes in published toxicity profiling What Does 5-Amino-1MQ Do in Research
Tissue repair research peptides are reference compounds studied in preclinical models of wound healing, tendon and ligament repair, and gut mucosal protection with BPC-157 and TB-500 as the two most investigated reagents in this space
Reported, but not confirmed Important limits Could relate to the compound, concentration, sterility, or injection method
US$ 25.67
US$ 23.61
US$ 23.85
US$ 24.92
