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10.1016/j.orcp.2021.02.002 45 RothM.OrijaI

185 In EGFR-mutant lung cancer, resistance to osimertinib is tightly linked to epigenetic regulation by the ATPase subunit SMARCA4 of the mSWI/SNF complex

Quantitative real-time PCR (qRT-PCR) was performed using 2 sybr Green qPCR MasterMix (Sevenbio, Beijing) and the ABI StepOnePlus real-time PCR system (Applied Biosystems, United States), with -actin as the internal reference

In the CNS, GLP-1 is produced by preproglucagon (Ppg) neurons with most cell bodies found in the nucleus tractus solitarius (NTS) 20