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Collagen Synthesis Regulation BPC-157 appears to influence genes associated with collagen production , which is foundational to: ligament studies tendon regeneration assays skin & dermal cellular repair models This is one of the reasons the peptide is heavily studied within orthopedic-related biochemical research

Injectable routes carry a particular concern for immunogenicity from peptide aggregation and impurities, and FDA noted the available certificates of analysis for AOD-9604 bulk drug substances did not consistently control for impurities, aggregates, or microbial limits

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Qi et al., 2021), however, to our knowledge this had not previously been shown in the cerebrovasculature