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For some patients, especially those with low energy tied to nutritional gaps, support can make it easier to stay consistent
Athletes should treat CLA the same way they treat creatine: as a compound that builds its effect through sustained, uninterrupted supplementation rather than producing an immediate noticeable response
Other avenues of intervention include amino acid synthesis pathways such as targeting the rate-limiting enzyme phosphoglycerate dehydrogenase (PHGDH) of the serine synthesis pathway 37,38 or indoleamine 2,3-dioxygenase 1 (IDO1), which generates kynurenine from tryptophan 39,40
Yoshida, M
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