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However, as the use of semaglutide has become more widespread, questions have arisen about its potential impact on the menstrual cycle in women

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GLP-1R agonists effects on cardiovascular events The first pieces of evidence of the potential clinical benefit of GLP-1 agonists have emerged recently, pointing to a decrease of major adverse cardiovascular and cerebrovascular events (MACCE) including stroke, MI, cardiac mortality, acute coronary syndrome, and revascularization procedures

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Whole-cell radioligand-binding assay Cells were seeded at a density of 30,000 cells/well into 96-well culture plates and incubated overnight in DMEM containing 5% FBS at 37 C in 5% CO 2