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Laboratory evaluation should include HbA1c, fasting glucose, lipid panel, liver function tests, and thyroid function to identify any underlying metabolic issues affecting response

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The vitamins exist to support enzymatic pathways that use those amino acids, not to replace them

Thus, integration of both hormones into a single molecule may not only maximize the metabolic efficacy of the individual signals, but allow also specific delivery of estrogen into GLP1 receptor-expressing cells, avoiding potential undesired effects of estrogen on reproductive tissues, as shown also in our studies