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10.1016/j.cell.2015.11.055 76

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Patients should be provided with clear safety advice , including when to temporarily discontinue SGLT2 inhibitors (during acute illness, dehydration, or 3 days before surgery), recognition of DKA symptoms (nausea, vomiting, abdominal pain, unusual fatigue), and management of genitourinary infections

Over 72 weeks patients without diabetes lost 15%, 19%, and 21% of body weight on the 5, 10, and 15 mg weekly SQ injections, respectively