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Presented for research literature review only Shabto JM et al
Despite manual corrections and deletions, only a few duplicate cases may exist [53, 54]
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its absence is informative but not disqualifying, especially when mechanistic and physiological evidence is otherwise robust ( Finally, insurmountable technical barrierssuch as inability to manufacture stable formulations, extreme immunogenicity, or lack of feasible delivery routesmay justify abandonment independent of biological plausibility
Validation of target protein-ligand complex structures Autodock 4.0 methodology was validated with the respective co-crystallized ligands of target proteins to ensure the virtual screening process
