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Some patients benefit from combination therapy or sequential medication trials to find optimal regimens
More work is needed to optimize these new strategies
Conclusion: Liraglutide and semaglutide protects skeletal muscle against obesity-induced muscle atrophy via the SIRT1 pathway
Wegovy is FDA-approved for weight loss and, in March 2024, it became the first FDA-approved treatment to reduce the risk of major cardiovascular events in adults with overweight or obesity
When consulting with a neurologist or specialist, patients must advocate for the correct diagnostic tools, as standard EMGs will not detect small fiber damage
![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
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