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doi:10.1073/pnas.48.1.9

5.1 Possible strategies of One-Two Punch therapy The inaugural investigations delving into the potential of this therapeutic strategy surfaced in the year 2017 [135]

So I think that we really need a broad thought about this

It is necessary to maintain a varied and balanced diet and a healthy lifestyle

However, the relatively small differences with exendin-asp3 suggest that additional mechanisms beyond receptor trafficking may be involved in the blunted insulin secretory response with this compound