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One of the earliest responses to aSAH is massive infiltration of the CNS by leukocytes, particularly neutrophils, which activate the innate immune response and stimulate resident microglia
Lysine is an essential amino acid
Notably, Gclc KO mice rapidly lose weight and reach humane endpoints early (Fig
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The lower activity of ChaC2 may be partly attributed to flexible loop 2, acting as a gating function to achieve specificity for GSH binding and regulate a constant GSH degradation rate
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