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Semaglutide Semaglutide is a medication that supports weight loss and blood sugar management by reducing appetite and promoting feelings of fullness

Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)

A history of serious hypersensitivity to tirzepatide or its excipients is a contraindication to its use, as stated in the FDA prescribing information

This is due to a lack of intrinsic factor

Van Boxtel, H