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Then, they were transfected with GSTM3 knockdown lentivirus (shGSTM3), scramble control lentivirus (shNC), GSTM3 overexpressing lentivirus (GSTM3-OE), and negative control (NC) lentivirus (GSTM3-NC) following the manufacturer's instructions

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Toxin exposure: Pollution, alcohol, smoking and chemicals consume glutathione during the detoxification process

Clinical trials to test for effects of GLP-1s on a range of novel outcomes including alcohol use disorder and Alzheimers disease are already underway

Statements Data availability statement The bulk RNA-seq data have been uploaded to the Gene Expression Omnibus database (GSE327373)