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Description

[1] It tested once-weekly cagrilintide across a dose range and compared it with both placebo and an active comparator (liraglutide 3.0 mg)

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Further exploration of the pathways through which ROS influences mitophagy to alter the progression of ischemic cardiomyopathy has shown that inhibition of Parkin-mediated mitophagy leads to excessive mitochondrial ROS accumulation, promoting myocardial injury and heart failure [85]

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