glp-1 drugs long term effects The Long-Term Side of Drugs: What We Know So Far WHO Issues Guidelines on GLP-1

Cardiovascular benefit for GLP-1RAs was shown in 2016 for liraglutide in the LEADER trial and semaglutide in the SUSTAIN 6 trial

Without PBS subsidy for obesity indications, patients pay full price: Wegovy: approximately $320$450 per month Saxenda: approximately $390$440 per month Mounjaro (off-label for weight loss): approximately $280$750 per month depending on dose PBS listing for obesity indications is an ongoing discussion, with health economists and advocacy groups pushing for subsidised access given the long-term healthcare costs associated with untreated obesity

doi:10.1038/s41392-024-01951-9 Uusitupa M, Khan TA, Viguiliouk E, et al

The GHK peptide is a tripeptide composed of three amino acids glycine, histidine, and lysine and complexed with a copper ion to form GHK-Cu

Burchell B (1999) Transformation reactions: glucuronidation