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HRs were generally on the order of magnitude of 0.85-0.90
The SURMOUNT-1 trial [1] established tirzepatide as the most effective weight loss medication currently available
Retatrutide does not yet have dedicated cardiovascular or renal outcome trials, though Phase 3 studies evaluating these endpoints are currently enrolling participants with expected completion in 2026
The SURMOUNT-2 study is a clinical study that enrolled 938 diabetic patients, receiving 10 mg or 15 mg of TZP or placebo
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